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Delay activity of specific prefrontal interneuron subtypes modulates memory-guided behavior


Authors: Tsukasa Kamigaki, Yang Dan
Publication: Nature Neuroscience
Date: April 24, 2017
Link to article: https://www.nature.com/articles/nn.4554


Memory-guided behavior requires maintenance of task-relevant information without sensory input, but the underlying circuit mechanism remains unclear. Calcium imaging in mice performing a delayed Go or No-Go task revealed robust delay activity in dorsomedial prefrontal cortex, with different pyramidal neurons signaling Go and No-Go action plans.

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