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Distinct speed dependence of entorhinal island and ocean cells, including respective grid cells


Authors: Chen Sun, Takashi Kitamura, Jun Yamamoto, Jared Martin, Michele Pignatelli, Lacey J. Kitch, Mark J. Schnitzer, and Susumu Tonegawa
Publication: PNAS
Date: July 13, 2015
Link to article: https://media.inscopix.com/cs/c/?cta_guid=07536edf-9a2b-4e0c-a803-2e25901a1d6a&…


Entorhinal–hippocampal circuits in the mammalian brain are crucial for an animal’s spatial and episodic experience, but the neural basis for different spatial computations remain unknown. Medial entorhinal cortex layer II contains pyramidal island and stellate ocean cells. Here, we performed cell type-specific Ca2+ imaging in freely exploring mice using cellular markers and a miniature head-mounted fluorescence microscope.

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