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Mesoscopic patterns of neural activity support songbird cortical sequences


Authors: Jeffrey E. Markowitz, William A. Liberti, Grigori Guitchounts, Tarciso Velho, Carlos Lois, Timothy J. Gardner
Publication: PLOS Biology
Date: June 3, 2015
Link to article: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002158


Time-locked sequences of neural activity can be found throughout the vertebrate forebrain in various species and behavioral contexts. From “time cells” in the hippocampus of rodents to cortical activity controlling movement, temporal sequence generation is integral to many forms of learned behavior. However, the mechanisms underlying sequence generation are not well known. Here, we describe a spatial and temporal organization of the songbird premotor cortical microcircuit that supports sparse sequences of neural activity.

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