New hope for improved antipsychotics

Efforts to develop more effective drugs for treating schizophrenia have received a significant boost with a groundbreaking study from the laboratory of Jones Parker at Northwestern University, published recently in Nature Neuroscience. Antipsychotic drugs, commonly prescribed for millions of people suffering from schizophrenia, often come with side effects and limited efficacy. However, this study offers

Decoding Calcium Dynamics

Decoding calcium dynamics in the hippocampus during memory retention and update with a miniscope.

How do we steadily recognize environments we are in while experiencing joy or possibly trauma? A recent publication by Dr. Kyogo Kobayashi and Dr. Naoki Matsuo from Kyushu University addressed this question of how animals code environmental information, i.e., spatial contextual memory in the brain, distinct from episodic memories. Using the Inscopix nVista miniscope, the


Hypothalamic calcium imaging data analysis reveals core differences in the neural coding of social behaviors

In an innovative new publication from the Anderson lab at Caltech, ‘An approximate line attractor in the hypothalamus encodes an aggressive state,’ Nair et al. use the Inscopix miniscope to investigate the population dynamics of the ventromedial hypothalamus (VMHvl) during aggressive behavior. This brain region was previously shown to cause attack behavior when optogenetically stimulated,

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