Author name: Daniel Stout

New hope for improved antipsychotics

Efforts to develop more effective drugs for treating schizophrenia have received a significant boost with a groundbreaking study from the laboratory of Jones Parker at Northwestern University, published recently in Nature Neuroscience. Antipsychotic drugs, commonly prescribed for millions of people suffering from schizophrenia, often come with side effects and limited efficacy. However, this study offers

Decoding Calcium Dynamics

Decoding calcium dynamics in the hippocampus during memory retention and update with a miniscope.

How do we steadily recognize environments we are in while experiencing joy or possibly trauma? A recent publication by Dr. Kyogo Kobayashi and Dr. Naoki Matsuo from Kyushu University addressed this question of how animals code environmental information, i.e., spatial contextual memory in the brain, distinct from episodic memories. Using the Inscopix nVista miniscope, the


Hypothalamic calcium imaging data analysis reveals core differences in the neural coding of social behaviors

In an innovative new publication from the Anderson lab at Caltech, ‘An approximate line attractor in the hypothalamus encodes an aggressive state,’ Nair et al. use the Inscopix miniscope to investigate the population dynamics of the ventromedial hypothalamus (VMHvl) during aggressive behavior. This brain region was previously shown to cause attack behavior when optogenetically stimulated,

Blood Flow Imaging with Inscopix Miniscopes

Simultaneous Blood Flow and Neural Activity Imaging with Inscopix Miniscopes

The Inscopix nVueTM system that was released last year has been a game changer for the in-vivo freely behaving imaging field and we are excited about the new application that enables simultaneous imaging of blood flow with cellular activity! If you aren’t familiar, the nVue system is a miniaturized microscope enabling the dual color imaging

Inscopix CNMF-E

Inscopix CNMF-E

Shay Neufeld, PhD is the Director of Data Products and Analytics at Inscopix, where he oversees a team of computational scientists, data engineers, and software engineers that work together to create software products for managing, processing, analyzing, and visualizing neuroscience and preclinical research data. Today is an exciting day for Inscopix, as it marks our

A deeper dive with photons

A deeper dive with photons

Recent breakthroughs in optical-based imaging in nonhuman primates promise to fundamentally advance our understanding of brain function and accelerate the development of next-generation brain-computer interfaces. Two new studies demonstrate complementary approaches for imaging the activity patterns of large populations of neurons in nonhuman primates (NHPs). Bollimunta*, Santacruz* & colleagues used a head-mounted one-photon miniature microscope

The Proview™ Express Probes Story

The Proview™ Express Probes Story

I’m excited to be writing for the blog again, this time to share my experiences at Inscopix working toward our goal of providing scientists with full solutions for their circuit neuroscience research. Given the multidisciplinary scientific expertise needed to successfully conduct studies at the level of circuits in behaving animals, we recognize how critical this

Dr. Ashley Ingiosi Talk About Biology of Brain While Sleeping

Coffee Break with Dr. Ashley Ingiosi

A postdoctoral researcher in Marcos Frank’s lab, she discusses her work examining astroglial biology in sleep and sleep homeostasis. What is your background and how did you become a circuit neuroscientist? I got BS degrees in Biopsychology and General Biology as well as a PhD in Neuroscience from the University of Michigan to study sleep

Enabling Circuit-Level Functional Readouts

Enabling circuit-level functional readouts in non-human primates for improved understanding of human brain function and CNS disease

Since this is my first blog post, I think a brief introduction is in order! I am currently the Director of Translational Science at Inscopix, overseeing our scientific programs with a translational and preclinical focus – which includes such activities as product and application development and scientific partnerships with academic and pharma/biotech groups. Before joining


Fear Memory

Believe it or not, this post was on our editorial calendar way back in January, and not even in our wildest imagination had we envisioned that at the time of publishing, life itself would become defined by the topic at hand- fear. Fear and anxiety are all too familiar to the world as a whole


Must-Read Circuit Neuroscience of 2020: Vol. I

We’re two months into 2020 and our beloved circuit neuroscience community has already served up so many treats that we’re wondering if it’s still the holidays! We’re excited to share with you our collection of top reads circuit neuroscience papers of 2020 thus far. You’ll find that each of them informs on fundamental biological functions

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