Method Archives - Inscopix, Inc.

Deconstruction of Vermal Cerebellum in Ramp Locomotion in Mice

Chenfei Lyu et al.
Advanced Science | November 14, 2022
The cerebellum is involved in encoding balance, posture, speed, and gravity during locomotion. However, most studies are carried out on flat surfaces, and little is known about cerebellar activity during free ambulation...

In vivo Calcium Imaging in Mouse Inferior Olive

Da Guo et al.
JOVE | June 10, 2021
Inferior olive (IO), a nucleus in the ventral medulla, is the only source of climbing fibers that form one of the two input pathways entering the cerebellum. IO has long been proposed to be crucial for motor control and...

Skin suturing and cortical surface viral infusion improves imaging of neuronal ensemble activity with head-mounted miniature microscopes

Xinjian Li et al.
Journal of Neuroscience Methods | August 19, 2017
In vivo optical imaging of neural activity provides important insights into brain functions at the single-cell level. Cranial windows and virally delivered calcium indicators are commonly used for imaging cortical...

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