Inscopix Publications

Publication Category: Medial entorhinal cortex (MEC)

Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer’s disease

Heng Zhou et al.
Scientific Reports | December 6, 2022
The Alzheimer’s disease-associated peptide amyloid-beta (Aβ) has been associated with neuronal hyperactivity under anesthesia, but clinical trials of anticonvulsants or neural system suppressors have, so far,...

Hippocampal neurons represent events as transferable units of experience

Chen Sun et al.
Nature Neuroscience | April 6, 2020
The brain codes continuous spatial, temporal and sensory changes in daily experience. Recent studies suggest that the brain also tracks experience as segmented subdivisions (events), but the neural basis for encoding...