Neurogenesis Archives - Inscopix, Inc.

Calcium imaging of adult-born neurons in freely moving mice

Alvaro Carrier-Ruiz et al.
STAR Protocols | March 19, 2021
Adult-born neurons (ABNs) in the dentate gyrus bestow unique cellular plasticity to the mammalian brain. We recently found that the activity of ABNs during sleep is necessary for memory consolidation. Here, we describe...

Lateral dispersion is required for circuit integration of newly generated dentate granule cells

Jia Wang et al.
Nature Communications | June 29, 2019
The process of circuit integration of newly-generated dentate granule cells of the hippo- campus has been presumed to be a dynamic process. In fact, little is known regarding the initial development of newly generated...

Neurovascular coupling in the dentate gyrus regulates adult hippocampal neurogenesis

Jia Shen et al.
Neuron | June 27, 2019
Newborn dentate granule cells (DGCs) are continuously generated in the adult brain. The mechanism underlying how the adult brain governs hippocampal neurogenesis remains poorly understood. In this study, we investigated...

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

Christoph Anacker et al.
Nature | June 27, 2018
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by environmental influences, and functionally implicated in behavioural responses to stress and antidepressants1,2,3,4. However, how...

Active dentate granule cells encode experience to promote the addition of adult-born hippocampal neurons

Gregory W. Kirschen et al.
The Journal of Neuroscience | April 3, 2017
The continuous addition of new dentate granule cells, exquisitely regulated by brain activity, renders the hippocampus plastic. However, how neural circuits encode experiences to impact the addition of adult-born...

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Publication Category: Neurogenesis