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Publication Category: Midbrain

Dopamine subsystems that track internal statesNature_0

James C. R. Grove et al.
Nature | July 13, 2022
Food and water are rewarding in part because they satisfy our internal needs. Dopaminergic neurons in the ventral tegmental area (VTA) are activated by gustatory rewards, but how animals learn to associate these oral...

Control of Non-REM Sleep by Midbrain Neurotensinergic NeuronsColor_dress_138

Peng Zhong et al.
Neuron | September 30, 2019
The periaqueductal gray (PAG) in the midbrain is known to coordinate behavioral and autonomic responses to threat and injury through its descending projections to the brainstem. Here, we show that neurotensin...

GABA and glutamate neurons in the VTA regulate sleep and wakefulnessColor_dress_117

Xiao Yu et al.
Nature Neuroscience | December 17, 2018
We screened for novel circuits in the mouse brain that promote wakefulness. Chemogenetic activation experiments and electroencephalogram recordings pointed to glutamatergic/nitrergic (NOS1) and GABAergic neurons in the...

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