Inscopix Publications

Publication Category: Midbrain

Dopamine neuron activity before action initiation gates and invigorates future movements

Joaquim Alves da Silva et al.
Nature | January 31, 2018
Deciding when and whether to move is critical for survival. Loss of dopamine neurons (DANs) of the substantia nigra pars compacta (SNc) in patients with Parkinson’s disease causes deficits in movement initiation and...

Regulation of REM and Non-REM Sleep by Periaqueductal GABAergic Neurons

Franz Weber et al.
Nature Communications | January 24, 2018
Mammalian sleep consists of distinct rapid eye movement (REM) and non-REM (NREM) states. The midbrain region ventrolateral periaqueductal gray (vlPAG) is known to be important for gating REM sleep, but the underlying...