Prefrontal cortex (PFC) Archives - Page 3 of 3

Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening

David J. Marcus et al.
Neuron | January 13, 2020
Functional coupling between the amygdala and the dorsomedial prefrontal cortex (dmPFC) has been implicated in the generation of negative affective states; however, the mechanisms by which stress increases amygdala-dmPFC...

A cortical-brainstem circuit predicts and governs compulsive alcohol drinking

Cody A. Siciliano et al.
Science | November 22, 2019
What individual differences in neural activity predict the future escalation of alcohol drinking from casual to compulsive? The neurobiological mechanisms that gate the transition from moderate to compulsive drinking...

Dopamine enhances signal-to-noise ratio in cortical-brainstem encoding of aversive stimuli

Caitlin M. Vander Weele et al.
Nature | November 7, 2018
Dopamine modulates medial prefrontal cortex (mPFC) activity to mediate diverse behavioural functions1,2; however, the precise circuit computations remain unknown. One potentially unifying model by which dopamine may...

Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data

Pengcheng Zhou et al.
eLife | February 22, 2018
In vivo calcium imaging through microendoscopic lenses enables imaging of previously inaccessible neuronal populations deep within the brains of freely moving animals. However, it is computationally challenging to...

Cell-type-specific activity in prefrontal cortex during goal-directed behavior

Lucas Pinto et al.
Neuron | February 7, 2015
The prefrontal cortex (PFC) plays a key role in controlling goal-directed behavior. Although a variety of task-related signals have been observed in the PFC, whether they are differentially encoded by various cell types...

Inscopix Publications

Publication Category: Prefrontal cortex (PFC)