Appetitive behaviors Archives - Page 2 of 3

Satb2 neurons in the parabrachial nucleus mediate taste perception

Brooke C. Jarvie et al.
Nature Communications | January 11, 2021
The neural circuitry mediating taste has been mapped out from the periphery to the cortex, but genetic identity of taste-responsive neurons has remained elusive. Here, we describe a population of neurons in the...

Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake

Takashi Matsuda et al.
Nature Communications | November 10, 2020
The control of water-intake behavior is critical for life because an excessive water intake induces pathological conditions, such as hyponatremia or water intoxication. However, the brain mechanisms controlling water...

Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption

Rong Gong et al.
Cell | August 24, 2020
Hunger and thirst have distinct goals but control similar ingestive behaviors, and little is known about neural processes that are shared between these behavioral states. We identify glutamatergic neurons in the...

REM sleep stabilizes hypothalamic representation of feeding behavior

Lukas T. Oesch et al.
PNAS | July 30, 2020
During rapid eye movement (REM) sleep, behavioral unresponsiveness contrasts strongly with intense brain-wide neural network dynamics. Yet, the physiological functions of this cellular activation remain unclear. Using...

Postingestive Modulation of Food Seeking Depends on Vagus-Mediated Dopamine Neuron Activity

Ana B. Fernandes et al.
Neuron | April 6, 2020
Postingestive nutrient sensing can induce food preferences. However, much less is known about the ability of postingestive signals to modulate food-seeking behaviors. Here we report a causal connection between...

A gut-to-brain signal of fluid osmolarity controls thirst satiation

Christopher A. Zimmerman et al.
Nature | March 27, 2019
Satiation is the process by which eating and drinking reduce appetite. For thirst, oropharyngeal cues have a critical role in driving satiation by reporting to the brain the volume of fluid that has been...

Parabrachial CGRP Neurons Establish and Sustain Aversive Taste Memories

Jane Y. Chen et al.
Neuron | October 18, 2018
Animals have innate preferences for tastes accompanying calorically rich foods and aversions to tastes associated with potentially spoiled or toxic foods. In addition, they possess learning mechanisms to modify feeding...

Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States

Paulius Viskaitis et al.
Cell Reports | December 19, 2017
Feeding requires the integration of homeostatic drives with emotional states relevant to food procurement in potentially hostile environments. The ventromedial hypothalamus (VMH) regulates feeding and anxiety, but how...

Oxytocin-receptor-expressing neurons in the parabrachial nucleus regulate fluid intake

Philip J. Ryan et al.
Nature Neuroscience | November 27, 2017
Brain regions that regulate fluid satiation are not well characterized, yet are essential for understanding fluid homeostasis. We found that oxytocin-receptor-expressing neurons in the parabrachial nucleus of mice...

Central amygdala circuits modulate food consumption through a positive-valence mechanism

Amelia M Douglass et al.
Nature Neuroscience | August 21, 2017
The complex behaviors underlying reward seeking and consumption are integral to organism survival. The hypothalamus and mesolimbic dopamine system are key mediators of these behaviors, yet regulation of appetitive and...

Neurons for hunger and thirst transmit a negative-valence teaching signal

J. Nicholas Betley et al.
Nature | April 27, 2016
Homeostasis is a biological principle for regulation of essential physiological parameters within a set range. Behavioural responses due to deviation from homeostasis are critical for survival, but motivational...

Hunger logic

et al.
Nature Neuroscience | May 26, 2015
Activation of AgRP-expressing ‘hunger’ neurons promotes robust feeding. Recent studies reveal the valence, dynamics and neural circuits engaged by AgRP neurons.

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Publication Category: Appetitive behaviors