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Neurons for hunger and thirst transmit a negative-valence teaching signal


Authors: J. Nicholas Betley, Shengjin Xu, Zhen Fang Huang Cao, Rong Gong, Christopher J. Magnus, Yang Yu, Scott M. Sternson
Publication: Nature
Date: April 27, 2016
Link to article: https://www.nature.com/articles/nature14416


Homeostasis is a biological principle for regulation of essential physiological parameters within a set range. Behavioural responses due to deviation from homeostasis are critical for survival, but motivational processes engaged by physiological need states are incompletely understood. We examined motivational characteristics of two separate neuron populations that regulate energy and fluid homeostasis by using cell-type-specific activity manipulations in mice.

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