Amygdala Archives - Page 3 of 3

An amygdalar neural ensemble that encodes the unpleasantness of pain

Gregory Corder et al.
Science | January 17, 2019
Pain is an unpleasant experience. How the brain’s affective neural circuits attribute this aversive quality to nociceptive information remains unknown. By means of time-lapse in vivo calcium imaging and neural...

Population coding of valence in the basolateral amygdala

Xian Zhang et al.
Nature Communications | December 5, 2018
The basolateral amygdala (BLA) plays important roles in associative learning, by representing conditioned stimuli (CSs) and unconditioned stimuli (USs), and by forming associations between CSs and USs. However, how such...

Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect

et al.
Molecular Psychiatry | November 30, 2018
Benzodiazepines (BZDs) have been a standard treatment for anxiety disorders for decades, but the neuronal circuit interactions mediating their anxiolytic effect remain largely unknown. Here, we find that systemic BZDs...

Simultaneous Optogenetics and Cellular Resolution Calcium Imaging During Active Behavior Using a Miniaturized Microscope

Alice M. Stamatakis et al.
Frontiers in Neuroscience | July 24, 2018
The ability to precisely monitor and manipulate neural circuits is essential to understand the brain. Advancements over the last decade in optical techniques such as calcium imaging and optogenetics have empowered...

Neuronal Representation of Social Information in the Medial Amygdala of Awake Behaving Mice

Ying Li et al.
Cell | October 26, 2017
The medial amygdala (MeA) plays a critical role in processing species- and sex-specific signals that trigger social and defensive behaviors. However, the principles by which this deep brain structure encodes social...

The central amygdala controls learning in the lateral amygdala

Kai Yu et al.
Nature Neuroscience | October 23, 2017
Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the formation of associations between sensory stimuli and an ensuing threat. However, how the central amygdala participates in such a...

Central amygdala circuits modulate food consumption through a positive-valence mechanism

Amelia M Douglass et al.
Nature Neuroscience | August 21, 2017
The complex behaviors underlying reward seeking and consumption are integral to organism survival. The hypothalamus and mesolimbic dopamine system are key mediators of these behaviors, yet regulation of appetitive and...

Neural ensemble dynamics underlying a long-term associative memory

Benjamin F. Grewe et al.
Nature | March 22, 2017
The brain’s ability to associate different stimuli is vital for long-term memory, but how neural ensembles encode associative memories is unknown. Here we studied how cell ensembles in the basal and lateral amygdala...

Distinct hippocampal pathways mediate dissociable roles of context in memory retrieval

Chun Xu et al.
Cell | October 20, 2016
Memories about sensory experiences are tightly linked to the context in which they were formed. Memory contextualization is fundamental for the selection of appropriate behavioral reactions needed for survival, yet the...

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Publication Category: Amygdala