Hippocampus Archives - Page 6 of 6

Distinct hippocampal pathways mediate dissociable roles of context in memory retrieval

Chun Xu et al.
Cell | October 20, 2016
Memories about sensory experiences are tightly linked to the context in which they were formed. Memory contextualization is fundamental for the selection of appropriate behavioral reactions needed for survival, yet the...

Ventral CA1 neurons store social memory

Teruhiro Okuyama et al.
Science | September 30, 2016
The medial temporal lobe, including the hippocampus, has been implicated in social memory. However, it remains unknown which parts of these brain regions and their circuits hold social memory. Here, we show that ventral...

Direct imaging of hippocampal epileptiform calcium motifs following kainic acid administration in freely behaving mice

Tamara K. Berdyyeva et al.
Frontiers in Neuroscience | February 29, 2016
Prolonged exposure to abnormally high calcium concentrations is thought to be a core mechanism underlying hippocampal damage in epileptic patients; however, no prior study has characterized calcium activity during...

Hippocampal ensemble dynamics timestamp events in long-term memory

Alon Rubin et al.
eLife | December 18, 2015
The capacity to remember temporal relationships between different events is essential to episodic memory, but little is currently known about its underlying mechanisms. We performed time-lapse imaging of thousands of...

Zolpidem reduces hippocampal neuronal activity in freely behaving mice: a large scale calcium imaging study with miniaturized fluorescence microscope

Tamara Berdyyeva et al.
PLOS ONE | November 5, 2014
Therapeutic drugs for cognitive and psychiatric disorders are often characterized by their molecular mechanism of action. Here we demonstrate a new approach to elucidate drug action on large-scale neuronal activity by...

Long-term dynamics of CA1 hippocampal place codes

Yaniv Ziv et al.
Nature Neuroscience | February 10, 2013
Using Ca2+ imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells’ place fields over weeks. Place coding was dynamic, as each day the ensemble...

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Publication Category: Hippocampus