Hypothalamus Archives - Page 3 of 3

A hypothalamus-habenula circuit controls aversion

Iakovos Lazaridis et al.
Molecular Psychiatry | February 12, 2019
Encoding and predicting aversive events are critical functions of circuits that support survival and emotional well-being. Maladaptive circuit changes in emotional valence processing can underlie the pathophysiology of...

A Hypothalamic Switch for REM and Non-REM Sleep

Kai-Siang Chen et al.
Neuron | February 22, 2018
Rapid eye movement (REM) and non-REM (NREM) sleep are controlled by specific neuronal circuits. Here we show that galanin-expressing GABAergic neurons in the dorsomedial hypothalamus (DMH) comprise separate...

Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States

Paulius Viskaitis et al.
Cell Reports | December 19, 2017
Feeding requires the integration of homeostatic drives with emotional states relevant to food procurement in potentially hostile environments. The ventromedial hypothalamus (VMH) regulates feeding and anxiety, but how...

Social behaviour shapes hypothalamic neural ensemble representations of conspecific sex

Ryan Remedios et al.
Nature | October 19, 2017
All animals possess a repertoire of innate (or instinctive1, 2) behaviours, which can be performed without training. Whether such behaviours are mediated by anatomically distinct and/or genetically specified neural...

Neurons for hunger and thirst transmit a negative-valence teaching signal

J. Nicholas Betley et al.
Nature | April 27, 2016
Homeostasis is a biological principle for regulation of essential physiological parameters within a set range. Behavioural responses due to deviation from homeostasis are critical for survival, but motivational...

Visualizing hypothalamic network dynamics for appetitive and consummatory behaviors

Joshua H. Jennings et al.
Cell | January 29, 2015
Optimally orchestrating complex behavioral states, such as the pursuit and consumption of food, is critical for an organism’s survival. The lateral hypothalamus (LH) is a neuroanatomical region essential for...

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Publication Category: Hypothalamus