James Alexander Taylor et al. Nature Communications | April 26, 2021
Cortical and limbic brain areas are regarded as centres for learning. However, how thalamic sensory relays participate in plasticity upon associative learning, yet support stable long-term sensory coding remains...
Giorgio Rizzi et al. Cell Reports | March 16, 2021
The firing activity of dorso-medial-striatal-cholinergic interneurons (dmCINs) is a neural correlate of classical conditioning. Tonically active, they pause in response to salient stimuli, mediating acquisition of...
Pablo Vergara et al. International Journal of Molecular Sciences | March 12, 2021
The mammalian hippocampal dentate gyrus is a unique memory circuit in which a subset of neurons is continuously generated throughout the lifespan. Previous studies have shown that the dentate gyrus neuronal population...
Thomas Akam et al. Neuron | November 4, 2020
Behavioral control is not unitary. It comprises parallel systems, model based and model free, that respectively generate flexible and habitual behaviors. Model-based decisions use predictions of the specific...
Paolo Botta et al. Cell | October 7, 2020
Exploration of novel environments ensures survival and evolutionary fitness. It is expressed through exploratory bouts and arrests that change dynamically based on experience. Neural circuits mediating exploratory...
Jessica C. Jimenez et al. Nature Communications | July 13, 2020
Ventral hippocampal CA1 (vCA1) projections to the amygdala are necessary for contextual fear memory. Here we used in vivo Ca2+ imaging in mice to assess the temporal dynamics by which ensembles of vCA1 neurons mediate...
Nathaniel R. Kinsky et al. Nature Communications | May 15, 2020
Trajectory-dependent splitter neurons in the hippocampus encode information about a rodent’s prior trajectory during performance of a continuous alternation task. As such, they provide valuable information for...
Liron Sheintuch et al. Current Biology | April 20, 2020
Hippocampal place cells selectively fire when an an- imal traverses a particular location and are consid- ered a neural substrate of spatial memory. Place cells were shown to change their activity patterns (remap)...
Chen Sun et al. Nature Neuroscience | April 6, 2020
The brain codes continuous spatial, temporal and sensory changes in daily experience. Recent studies suggest that the brain also tracks experience as segmented subdivisions (events), but the neural basis for encoding...
Hirotaka Asai et al. Molecular Brain | January 20, 2020
Clustered protocadherins (Pcdhs), a large group of adhesion molecules, are important for axonal projections and dendritic spread, but little is known about how they influence neuronal activity. The Pcdhβ cluster is...
