Learning and Memory Archives - Page 5 of 6

Encoding of Danger by Parabrachial CGRP Neurons

Carlos A. Campos et al.
Nature | March 21, 2018
Animals must respond to various threats to survive. Neurons that express calcitonin gene-related peptide in the parabrachial nucleus (CGRPPBN neurons) relay sensory signals that contribute to satiation and pain-induced...

Reward-Predictive Neural Activities in Striatal Striosome Compartments

Tomohiko Yoshizawa et al.
eNeuro | January 29, 2018
The striatum has been shown to play a critical role in reward prediction. It is composed of two neurochemically and anatomically distinct compartments known as the striosomes and the matrix. The striosomes comprise only...

Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context

Akiko Wagatsuma et al.
PNAS | December 26, 2017
The memory for a new episode is formed immediately upon experience and can last up to a lifetime. It has been shown that the hippocampal network plays a fundamental role in the rapid acquisition of a memory of a...

Tracking the Same Neurons across Multiple Days in Ca2+ Imaging Data

Liron Sheintuch et al.
Cell Reports | November 24, 2017
Ca2+ imaging techniques permit time-lapse recordings of neuronal activity from large populations over weeks. However, without identifying the same neurons across imaging sessions (cell registration), longitudinal...

The central amygdala controls learning in the lateral amygdala

Kai Yu et al.
Nature Neuroscience | October 23, 2017
Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the formation of associations between sensory stimuli and an ensuing threat. However, how the central amygdala participates in such a...

Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories

Dheeraj S. Roy et al.
Cell | August 17, 2017
The formation and retrieval of a memory is thought to be accomplished by activation and reactivation, respectively, of the memory-holding cells (engram cells) by a common set of neural circuits, but this hypothesis has...

Multi-layer cortical calcium imaging in freely moving mice with prism probes and miniaturized fluorescence microscopy

Srishti Gulati et al.
JoVE | June 13, 2017
In vivo circuit and cellular level functional imaging is a critical tool for understanding the brain in action. High resolution imaging of mouse cortical neurons with two-photon microscopy has provided unique insights...

Identification of a motor-to-auditory pathway important for vocal learning

Todd F Roberts et al.
Nature Neuroscience | May 15, 2017
Learning to vocalize depends on the ability to adaptively modify the temporal and spectral features of vocal elements. Neurons that convey motor-related signals to the auditory system are theorized to facilitate vocal...

Engrams and circuits crucial for systems consolidation of a memory

Takashi Kitamura et al.
Science | April 7, 2017
Episodic memories initially require rapid synaptic plasticity within the hippocampus for their formation and are gradually consolidated in neocortical networks for permanent storage. However, the engrams and circuits...

Neural ensemble dynamics underlying a long-term associative memory

Benjamin F. Grewe et al.
Nature | March 22, 2017
The brain’s ability to associate different stimuli is vital for long-term memory, but how neural ensembles encode associative memories is unknown. Here we studied how cell ensembles in the basal and lateral amygdala...

Ventral CA1 neurons store social memory

Teruhiro Okuyama et al.
Science | September 30, 2016
The medial temporal lobe, including the hippocampus, has been implicated in social memory. However, it remains unknown which parts of these brain regions and their circuits hold social memory. Here, we show that ventral...

Calcium imaging of basal forebrain activity during innate and learned behavio

Thomas C. Harrison et al.
Frontiers in Neural Circuits | May 9, 2016
The basal forebrain (BF) plays crucial roles in arousal, attention, and memory, and its impairment is associated with a variety of cognitive deficits. The BF consists of cholinergic, GABAergic, and glutamatergic...

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Publication Category: Learning and Memory