News and commentary from the Inscopix community Preclinical Drug Development

Parkinson’s disease (PD) is a neurological disorder that affects 6 hundred thousand to more than 1 million people in the United States, or over 6 million worldwide, making it the second most prevalent brain disease behind Alzheimer’s. This disease presents differently in every individual but is typically marked by motor symptoms such as resting tremors,


From behavioral studies on learning and memory to sleep-wakefulness, 2023 was a year full of researchers uncovering…

Melissa Martin


Image: Data courtesy of Jones Parker lab – Northwestern University. Efforts to develop more effective drugs for treating…

Jonathan Zapata


Pregnancy and childbirth are extraordinary experiences that profoundly change a mother’s life. But did you know that the…

Yasaman Farshchi

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In an innovative new publication from the Anderson lab at Caltech, ‘An approximate line attractor in the hypothalamus encodes an aggressive state,’ Nair et al. use the Inscopix miniscope to investigate the population dynamics of the ventromedial hypothalamus (VMHvl) during aggressive behavior. This brain region was previously shown to cause attack behavior when optogenetically stimulated,

Peter Schuette


The Inscopix nVue™ system that was released last year has been a game changer for the in-vivo freely behaving imaging field and we are excited about the new application that enables simultaneous imaging of blood flow with cellular activity! If you aren’t familiar, the nVue system is a miniaturized microscope enabling the dual color imaging

Srishti Gulati


Today is an exciting day for Inscopix, as it marks our first release of a data processing algorithm for everyone to freely use, evaluate, and contribute to. As those in the circuit neuroscience field can appreciate, transforming calcium imaging data from pixels to neurons can be a difficult and cumbersome process. One approach — Constrained

Shay Neufeld


Recent breakthroughs in optical-based imaging in nonhuman primates promise to fundamentally advance our understanding of brain function and accelerate the development of next-generation brain-computer interfaces. Recent breakthroughs in neuroscience, engineering and medicine have set the stage for entirely new ways to treat brain disorders and restore physical and cognitive abilities. Implantable medical devices have the

Jonathan Nassi and Eric Trautmann


I’m excited to be writing for the blog again, this time to share my experiences at Inscopix working toward our goal of providing scientists with full solutions for their circuit neuroscience research. Given the multidisciplinary scientific expertise needed to successfully conduct studies at the level of circuits in behaving animals, we recognize how critical this

Jonathan Nassi


A postdoctoral researcher in Marcos Frank’s lab, she discusses her work examining astroglial biology in sleep and sleep homeostasis. What is your background and how did you become a circuit neuroscientist? I got BS degrees in Biopsychology and General Biology as well as a PhD in Neuroscience from the University of Michigan to study sleep

Sushmitha Gururaj

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